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David Ferrer beat Thomaz Bellucci 6-1, 6-2 to reach the Valencia semi-finals where he will face Andy Murray.
With this win, Ferrer joins Roger Federer (986 wins), Rafael Nadal (706) and Lleyton Hewitt (611) in the modern era 600-win club.
"I’m most proud of all the years that I’ve been able to stay among the best players in the world," said Ferrer.
"There have been important tournaments that I’ve won, and that I’ve been proud of, but what I’m most proud of is to have been able to maintain this stability for all these years.
“I’m proud that this 600th victory was at home. I want to thank all the people that have been with me along the way.”